Abstract
Hydrogel-based orthopedic implants represent a new class of bioresponsive, minimally invasive, and tissue-friendly materials capable of revolutionizing joint repair. Their unique ability to mimic cartilage extracellular matrix, incorporate stem cells, and deliver therapeutic biomolecules has positioned them as leading candidates for next-generation orthopedic interventions. This paper explores intelligent hydrogel systems—including stimuli-responsive, injectable, and nanocomposite-enhanced formulations—designed for cartilage regeneration, meniscal repair, and subchondral restoration. Emphasis is placed on material design principles, biomechanical performance, clinical translation challenges, and future prospects such as 4D hydrogels and AI-assisted implant design. Conceptual figures and analytical tables are provided to summarize emerging hydrogel types, properties, and orthopedic applications.
